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Genetic Coeliac Disease Test

What is it?

A Genetic Coeliac Disease Test is a fast, accurate back-to-lab test that can tell individuals whether they carry the genes linked to coeliac disease.

Coeliac disease is an autoimmune disease that develops over time because of a sensitivity to gluten, a protein found in certain cereal grains including wheat, rye, and barley, and commonly used in food products including bread, cereal, and pasta.

The Genetic Coeliac Disease Test is non-invasive, with only a cheek swab sample required, and uses Human Leukocyte Antigen (HLA) typing to confirm or rule out the potential of developing coeliac disease by analysing six DNA markers for the HLA-DQ2 and HLA-DQ8 genes.

Why is this test useful?

Experts believe that only around 30% per cent of people with coeliac disease are correctly diagnosed, and that most cases go undiagnosed or are misdiagnosed as irritable bowel syndrome (IBS).

The disease runs in families. It can start at any age, although most people are diagnosed between the ages of 50 and 70. Women are three times more likely than men to develop coeliac disease.

If undiagnosed or untreated, coeliac disease can lead to severe complications. These can include osteoporosis, neurological diseases, anaemia, and even intestinal lymphoma and bowel cancer.

However, the sooner that coeliac disease is diagnosed, the sooner it can be effectively managed with
a gluten-free diet.

Who should take this test?

The test is useful for:

  • Individuals experiencing symptoms including diarrhoea, constipation, bloating, flatulence, indigestion, regular mouth ulcers, nausea, and fatigue
  • People with close family members who have been diagnosed with coeliac disease. People with coeliac disease have a higher risk of passing the disease down to first-degree relatives (i.e. parents to children)
  • Individuals who have been following a gluten-free diet, and want to rule out the risk of developing coeliac disease, so that they can seek the correct treatment.

Samples required

A simple cheek swab is all that is required from the person taking part in the test.

 

Price £125.00 

Results

The test results will show either a negative result, or that the person is at very low, low, moderate or high risk of developing coeliac disease.

 

If the test results show that one or both genes (HLA-DQ2 and/or HLA-DQ8) are present…

  • The sample donor could be at risk of developing coeliac disease in the future
  • The test report will show whether the individual is at very low, low, moderate or high risk of developing coeliac disease, depending on which genes they have.

However, having these genes does not guarantee that a person will develop coeliac disease, or indicate that they are currently suffering from it.

 

If the test results show that neither of the genes are present…

  • The sample donor is unlikely to develop coeliac disease in the future.

E-mail

For all general enquiries or requests please contact us using the email above. We will get back to you within 24 hours.

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The Fitzrovia Hospital, 13-14 Fitzroy Square, London, W1T 6AH

Monday - Friday: 8:00am - 4:00 pm
Saturday: Closed
Sunday: Closed

02035323471

Need to a quick response? Contact us using the numbers above. We are available to speak during our usual opening hours.

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